CodonO webserver is implemented for synonymous codon usage bias analyses within and across genomes. CodonO measures Synonymous Codon Usage Order (SCUO) in a genomic scale by connecting directly GenBank genomic database. CodonO plots SCUO and GC compositions. The webserver display the results for multiple genomes in the same plots. It identifies the outliers for a genome or a group of sequences based on Tukey statistical analysis. It also compare whether codon usage biases are similar between genomes using Wilcoxon Two Sample Test. The CodonO webserver provides all of pre-calculated SCUO and GC compositions for each genome, which can be batch downloaded for the users' perference analyses. The standalone CodonO is freely avaiable at http://sysbio.cvm.msstate.edu/CodonO/downloads/.

 

About Codon Usage Bias

About Synonymous Codon Usage Order (SCUO)